LOUISVILLE, Ky. -- No. 19 Louisville is facing a different kind of opponent in its opener against upstart Charlotte after recently kicking off the season with the likes of Miami and Auburn.The Cardinals are 40-point favorites in Thursday nights matchup against the 49ers, who begin their second season of FBS play trying to end a 10-game losing streak. Thats asking a lot of Charlotte, which will face its first ranked foe. Add in that Louisville returns several players from a squad that won eight of its final 10 games, including the Music City Bowl.Louisville began the season 0-3, its worst opening since 1984 and players are determined to start better this season. With consecutive Atlantic Coast Conference games against Syracuse and No. 4 Florida State the next two weeks, the Cardinals hope all phases -- offense, defense and special teams -- click in a game theyre expected to dominate.Its no different, senior defensive tackle DeAngelo Brown said this week. Weve just got to focus on ourselves, what were doing as a team and do the things weve been coached to do.Louisville enters with more offensive stability thanks to the maturation of dual-threat sophomore quarterback Lamar Jackson. Four of five linemen are back along with a seasoned receiver corps that has added former Cardinals quarterback Reggie Bonnafon to the starting lineup.Brown (40 tackles) is among several leaders on a Cardinals defense that also features leading tackler Keith Kelsey (107) and Devonte Fields (11 sacks). Not to mention, a veteran secondary.Charlotte also has experience that it hopes will translate into a more competitive season. The roster features 15 returning starters and more than two dozen seniors who helped the 49ers win their FBS debut against Georgia State before growing pains kicked in.Charlotte coach Brad Lambert hopes his team savors and builds on playing a Top 25 opponent- even if they are huge underdogs.Its a good challenge for us but I like where our guys are, Lambert said. What do we have to lose? Its going to be fun. We have an old team and an experienced team. ... Well go out, have some fun and enjoy the moment.---Here are other things to watch when Charlotte visits No. 19 Louisville:JACKSONS ACTIONS: Louisville sophomore quarterback Lamar Jackson came a long way after having his first career pass intercepted on a failed trick play. Despite combining for 2,800 yards offensively with 23 touchdowns last season he vows to trust his protection more, recognize coverages better and become a better pocket passer. Coach Bobby Petrino is curious to see if those improvements counter Charlottes multiple defensive fronts. They will probably try to come after us, try to give him some different looks and bring pressure, Petrino said, so it will be good to see what happens.49ERS OFFENSE: Senior RB Kalif Phillips has rushed for school records of 3,113 career yards and 37 touchdowns -- including 961 last season. Charlotte will unveil a new QB in Kevin Olsen, a Miami signee who won the job last spring. He played last season at Riverside (California) City College.CARDS KICKING GAME: Sophomore Evan OHara takes over as Louisvilles place kicker while redshirt freshman Mason King handles punting duties. OHara has the tough job of succeeding reliable John Wallace, but Petrino said he has shown good height, distance and consistency in fall camp. King meanwhile has shown a quick release and good hang time while being pushed by fellow freshman Austin Johnson.OPENING BIDS: Last seasons loss to Auburn in Atlanta was Petrinos first opening-game defeat in 11 lifetime contests. He has won five of six openers in two stints with Louisville.---Follow Gary B. Graves on Twitter at www.Twitter.com/GaryBGraves and APs College Football page at collegefootball.ap.org. Air Max 270 Flyknit Work Blue .S. Open champion Justin Rose birdied the first hole with a blind shot he hit to a foot of the pin, and he stayed in front Tuesday until he completed a 4-under 67 for a two-shot lead over Jason Dufner in PGA Grand Slam of Golf. Air Max 270 Spirit Teal . 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